FOXO6-AS1

Across TCGA pan-cancer cohorts, FOXO6-AS1 RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated FOXO6-AS1 data layer.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher FOXO6-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated FOXO6-AS1 expression acts as an unfavorable survival marker, although some lineages such as CESC and DLBC show a favorable association.

UCEC, CESC, and KIRC are the cancer types where FOXO6-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Quartile	All	0.861	0.931	.001	82	view →
CESC	OS	Tertile	IV	0.829	0.250	.003	36	view →
KIRC	DFS	Median	II,III,IV	0.406	0.631	<.001	36	view →
DLBC	DFS	Median	All	0.816	0.419	.003	23	view →
STAD	DFS	Quartile	All	0.761	0.612	.010	19	view →
PCPG	DFS	Quartile	All	0.980	0.763	.001	15	view →
PRAD	DFS	Quartile	All	0.826	0.936	.004	14	view →
KIRP	DFS	Median	All	0.882	0.627	.025	10	view →
LIHC	OS	Tertile	III,IV	0.414	0.692	.012	9	view →
READ	OS	Tertile	III,IV	0.632	0.262	.002	7	view →
OV	OS	Median	IV	0.583	0.905	.004	6	view →
BRCA	OS	Quartile	II,III,IV	0.733	0.563	.018	5	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

FOXO6-AS1–UCEC (DFS)

Open the UCEC breakdown →