FOXN3-AS2

Across TCGA pan-cancer cohorts, FOXN3-AS2 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of FOXN3-AS2’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where FOXN3-AS2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types FOXN3-AS2 is over-expressed in tumor, although a few such as LUAD and COAD show the opposite, repressed pattern.

KIRC, LUAD, and COAD are the cancer types where FOXN3-AS2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in FOXN3-AS2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	All	+0.014	<.001	10	view →
LUAD	All	III,IV	−0.044	.048	1	view →
COAD	All	III,IV	−0.027	.040	1	view →
KICH	Female	II,III,IV	+0.024	.016	1	view →
LUSC	Female	All	−0.021	.040	1	view →
LIHC	All	All	+0.005	.023	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

FOXN3-AS2–KIRC

Open the KIRC breakdown →