FOXN2

Across TCGA cell cohorts, FOXN2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,177 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible FOXN2-associated GO terms across cancer lineages are Transcription initiation at RNA polymerase I promoter, Centrosome cycle, and Microtubule organizing center organization. Each is linked with FOXN2 in more than 13 cancer types. Because this analysis shows association rather than direction, both FOXN2-to-partner and partner-to-FOXN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Transcription initiation at RNA polymerase I promoter grouped by FOXN2-low versus FOXN2-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXN2→partner) and Y-score (partner→FOXN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Transcription initiation at RNA polymerase I promoter →	+0.102	+1.066	<.001	<.001	3	14
BREAST	Centrosome cycle →	+0.095	+0.974	<.001	<.001	3	13
LARGE_INTESTINE	Microtubule organizing center organization →	+0.077	+0.827	<.001	<.001	3	13
SOFT_TISSUE	Regulation of sister chromatid cohesion →	+0.111	+0.808	<.001	<.001	3	13
BREAST	Nuclear pore complex assembly →	+0.117	+0.789	.001	<.001	3	12
BLOOD_Lymphoma	Transcription by RNA polymerase I →	+0.084	+0.971	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,177 associations by consensus.

Transcription initiation at RNA polymerase I promoter by FOXN2 expression — BLOOD_Lymphoma

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