FOXN1

Across TCGA cell cohorts, FOXN1 RNA expression is significantly associated with the go_rna of many other GO terms, with 981 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible FOXN1-associated GO terms across cancer lineages are Response to indole-3-methanol, Regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, and Cellular response to indole-3-methanol. Each is linked with FOXN1 in more than 6 cancer types. Because this analysis shows association rather than direction, both FOXN1-to-partner and partner-to-FOXN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to indole-3-methanol grouped by FOXN1-low versus FOXN1-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXN1→partner) and Y-score (partner→FOXN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Response to indole-3-methanol →	+0.231	+0.175	<.001	.004	3	7
UPPER_AERODIGESTIVE_TRACT	Regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay →	+0.099	+1.074	<.001	<.001	3	6
BREAST	Cellular response to indole-3-methanol →	+0.197	+0.230	<.001	.001	3	6
LUNG_NSCLC_LUAD	Keratinocyte development →	-0.306	-0.083	<.001	.003	3	5
URINARY_TRACT	Urea transmembrane transport →	+1.672	+0.330	<.001	.004	3	5
BREAST	Protein localization to plasma membrane →	+0.049	+0.177	.008	.004	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 981 associations by consensus.

Response to indole-3-methanol by FOXN1 expression — BREAST

Explore this box plot interactively →