FOXM1

Across TCGA patient cohorts, FOXM1 RNA expression is significantly associated with the protein abundance of many other proteins, with 26,327 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible FOXM1-associated proteins across cancer lineages are RRM2, SMC2, and SMC4. Each is linked with FOXM1 in more than 9 cancer types. Because this analysis shows association rather than direction, both FOXM1-to-partner and partner-to-FOXM1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FOXM1 versus RRM2 in LUAD, with a Pearson correlation of 0.68.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXM1→partner) and Y-score (partner→FOXM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RRM2 →	+0.973	+1.396	<.001	<.001	3	10
GBM	SMC2 →	+0.794	+1.243	<.001	<.001	3	10
GBM	SMC4 →	+0.774	+1.262	<.001	<.001	3	10
LUAD	KPNA2 →	+0.759	+1.329	<.001	<.001	3	10
OV	MCM3 →	+0.929	+1.297	<.001	<.001	3	10
LUAD	MCM5 →	+0.897	+1.386	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 26,327 associations by consensus.

FOXM1 vs RRM2 — LUAD

Explore this scatter interactively →