Across TCGA patient cohorts, FOXL2NB mutation is significantly associated with the total protein of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FOXL2NB-associated genes across cancer lineages are Ku80, Claudin-7, and C-Raf. Each is linked with FOXL2NB in more than 1 cancer types. Because this analysis shows association rather than direction, both FOXL2NB-to-partner and partner-to-FOXL2NB results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXL2NB→partner) and Y-score (partner→FOXL2NB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Ku80 →	+0.303	+3.183	.019	.010	3	1
UCEC	Claudin-7 →	-0.693	-3.169	.012	.020	3	1
UCEC	C-Raf →	+0.290	+3.169	<.001	.020	2	1
UCEC	AMPK_alpha →	-0.206	-3.169	.049	.020	1	1
UCEC	STAT3_pY705 →	-0.561	-3.169	<.001	.020	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

FOXL2NB survival (RNA) · tumor vs normal (RNA) · all FOXL2NB data types