FOXL1

Across TCGA cell cohorts, FOXL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,680 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible FOXL1-associated GO terms across cancer lineages are Regulation of cell-matrix adhesion, Negative regulation of response to wounding, and Extracellular matrix organization. Each is linked with FOXL1 in more than 10 cancer types. Because this analysis shows association rather than direction, both FOXL1-to-partner and partner-to-FOXL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of cell-matrix adhesion grouped by FOXL1-low versus FOXL1-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXL1→partner) and Y-score (partner→FOXL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Regulation of cell-matrix adhesion →	+0.137	+2.467	.001	.006	3	11
OESOPHAGUS	Negative regulation of response to wounding →	+0.094	+1.739	.002	<.001	3	10
BREAST	Extracellular matrix organization →	+0.127	+0.933	<.001	.001	3	10
BREAST	Cell-substrate adhesion →	+0.106	+1.043	<.001	<.001	3	10
BREAST	Extracellular structure organization →	+0.126	+0.933	<.001	.001	3	10
OVARY	Blood coagulation →	+0.074	+1.206	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,680 associations by consensus.

Regulation of cell-matrix adhesion by FOXL1 expression — LIVER

Explore this box plot interactively →