FOXK1

Across TCGA patient cohorts, FOXK1 protein abundance is significantly associated with the RNA expression of many other genes, with 17,151 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FOXK1-associated genes across cancer lineages are EIF3B, WIPI2, and ZNF12. Each is linked with FOXK1 in more than 8 cancer types. Because this analysis shows association rather than direction, both FOXK1-to-partner and partner-to-FOXK1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FOXK1 versus EIF3B in LUAD, with a Pearson correlation of 0.69.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXK1→partner) and Y-score (partner→FOXK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	EIF3B →	+0.634	+0.303	<.001	<.001	3	9
LUAD	WIPI2 →	+0.460	+0.312	<.001	<.001	3	8
OV	ZNF12 →	+0.732	+0.423	<.001	<.001	3	8
OV	RNF216P1 →	+0.493	+0.451	<.001	<.001	3	8
HNSC	COX19 →	+0.622	+0.258	<.001	<.001	3	8
LSCC	RP9 →	+0.457	+0.284	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,151 associations by consensus.

FOXK1 vs EIF3B — LUAD

Explore this scatter interactively →