FOXK1

Across TCGA cell cohorts, FOXK1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,620 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FOXK1-associated GO terms across cancer lineages are Viral translational termination-reinitiation, Chromosome localization to nuclear envelope involved in homologous chromosome segregation, and Negative regulation of transcription initiation by RNA polymerase II. Each is linked with FOXK1 in more than 14 cancer types. Because this analysis shows association rather than direction, both FOXK1-to-partner and partner-to-FOXK1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Viral translational termination-reinitiation grouped by FOXK1-low versus FOXK1-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXK1→partner) and Y-score (partner→FOXK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Viral translational termination-reinitiation →	+0.104	+1.088	<.001	<.001	3	15
BLOOD_Myeloma	Chromosome localization to nuclear envelope involved in homologous chromosome segregation →	+0.234	+0.943	<.001	<.001	3	15
LARGE_INTESTINE	Negative regulation of transcription initiation by RNA polymerase II →	+0.137	+0.908	<.001	<.001	3	14
BLOOD_Myeloma	Meiotic attachment of telomere to nuclear envelope →	+0.123	+1.013	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Endosomal transport →	+0.052	+0.804	.002	.001	3	14
LARGE_INTESTINE	Negative regulation of DNA-templated transcription initiation →	+0.137	+0.908	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,620 associations by consensus.

Viral translational termination-reinitiation by FOXK1 expression — BLOOD_Lymphoma

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