Across TCGA patient cohorts, FOXJ3 mutation is significantly associated with the total protein of many other genes, with 45 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FOXJ3-associated genes across cancer lineages are mTOR_pS2448, Shc_pY317, and 14-3-3_beta. Each is linked with FOXJ3 in more than 1 cancer types. Because this analysis shows association rather than direction, both FOXJ3-to-partner and partner-to-FOXJ3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXJ3→partner) and Y-score (partner→FOXJ3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	mTOR_pS2448 →	-0.105	-1.912	.013	.004	3	2
UCEC	Shc_pY317 →	-0.173	-1.938	<.001	.001	3	2
UCEC	14-3-3_beta →	-0.079	-1.973	.005	.008	3	1
UCEC	eEF2 →	+0.288	+1.222	.004	.011	3	1
UCEC	EGFR_pY1068 →	-0.222	-1.716	.001	.003	3	1
UCEC	eIF4E →	+0.190	+2.920	.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 45 associations by consensus.

Exploration

FOXJ3 survival (RNA) · tumor vs normal (RNA) · all FOXJ3 data types