Across TCGA cell cohorts, FOXJ3 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FOXJ3-associated genes across cancer lineages are SEMG2, BPY2, and BPY2B. Each is linked with FOXJ3 in more than 1 cancer types. Because this analysis shows association rather than direction, both FOXJ3-to-partner and partner-to-FOXJ3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXJ3→partner) and Y-score (partner→FOXJ3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	SEMG2 →	+0.425	+2.878	.002	.009	3	1
LARGE_INTESTINE	BPY2 →	+0.012	+3.700	<.001	.009	3	1
LARGE_INTESTINE	BPY2B →	+0.012	+3.700	<.001	.009	3	1
LARGE_INTESTINE	BPY2C →	+0.012	+3.700	<.001	.009	3	1
LARGE_INTESTINE	TKTL2 →	+0.038	+3.187	.002	.006	2	1
LARGE_INTESTINE	SMIM33 →	+0.806	+3.426	<.001	.007	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

Exploration

FOXJ3 survival (RNA) · tumor vs normal (RNA) · all FOXJ3 data types