FOXJ1

Across TCGA cell cohorts, FOXJ1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,136 significant associations in total. BONE shows the largest number of these associations.

The most reproducible FOXJ1-associated GO terms across cancer lineages are Negative regulation of RNA splicing, Negative regulation of transcription elongation by RNA polymerase II, and Nucleoside triphosphate biosynthetic process. Each is linked with FOXJ1 in more than 6 cancer types. Because this analysis shows association rather than direction, both FOXJ1-to-partner and partner-to-FOXJ1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of RNA splicing grouped by FOXJ1-low versus FOXJ1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXJ1→partner) and Y-score (partner→FOXJ1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Negative regulation of RNA splicing →	+0.102	+0.246	<.001	.001	3	7
BREAST	Negative regulation of transcription elongation by RNA polymerase II →	+0.078	+1.041	.001	.004	3	7
BONE	Nucleoside triphosphate biosynthetic process →	+0.113	+0.271	<.001	.004	3	7
BONE	Ribonucleoside triphosphate biosynthetic process →	+0.106	+0.219	<.001	.004	3	7
BLOOD_Myeloma	Cytoplasmic translational initiation →	+0.070	+0.890	<.001	.007	3	7
BREAST	Regulation of myoblast fusion →	+0.087	+1.426	.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,136 associations by consensus.

Negative regulation of RNA splicing by FOXJ1 expression — BONE

Explore this box plot interactively →