FOXG1-AS1

Across TCGA pan-cancer cohorts, FOXG1-AS1 RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated FOXG1-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher FOXG1-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated FOXG1-AS1 expression acts as an unfavorable survival marker, although some lineages such as LGG show a favorable association.

KIRC, LUAD, and UVM are the cancer types where FOXG1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Tertile	All	0.506	0.650	.001	108	view →
LUAD	OS	Tertile	II,III,IV	0.532	0.745	.002	87	view →
UVM	OS	Tertile	II,III,IV	0.213	0.718	.002	81	view →
KIRP	DFS	Tertile	All	0.313	0.667	<.001	69	view →
BRCA	DFS	Tertile	III,IV	0.711	0.886	.006	42	view →
THCA	OS	Tertile	IV	0.677	0.972	<.001	27	view →
LGG	DFS	Median	All	0.886	0.763	.001	25	view →
MESO	DFS	Quartile	IV	0.079	0.447	<.001	23	view →
KICH	OS	Tertile	III,IV	0.178	0.847	<.001	18	view →
PAAD	OS	Tertile	All	0.409	0.601	.008	9	view →
ESCA	DFS	Tertile	All	0.384	0.542	.023	7	view →
OV	OS	Tertile	III,IV	0.765	0.849	.035	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

FOXG1-AS1–KIRC (OS)

Open the KIRC breakdown →