Across TCGA patient cohorts, FOXE3 mutation is significantly associated with the RNA expression of many other genes, with 159 significant associations in total. COAD shows the largest number of these associations.

The most reproducible FOXE3-associated genes across cancer lineages are NUTF2P3, CXCL1P1, and ATG3P1. Each is linked with FOXE3 in more than 1 cancer types. Because this analysis shows association rather than direction, both FOXE3-to-partner and partner-to-FOXE3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXE3→partner) and Y-score (partner→FOXE3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	NUTF2P3 →	+0.471	+3.958	<.001	.001	3	2
BLCA	CXCL1P1 →	+0.264	+7.640	<.001	.009	3	2
UCEC	ATG3P1 →	+0.106	+4.538	<.001	.006	3	2
BLCA	MIR4311 →	+0.477	+7.640	<.001	.009	3	1
BLCA	MIR548H5 →	+0.416	+7.640	<.001	.009	3	1
BLCA	MIR6134 →	+0.448	+7.640	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 159 associations by consensus.

Exploration

FOXE3 survival (RNA) · tumor vs normal (RNA) · all FOXE3 data types