Across TCGA cell cohorts, FOXE3 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,778 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FOXE3-associated GO terms across cancer lineages are Negative regulation of RNA splicing, Purine ribonucleoside triphosphate metabolic process, and Negative regulation of mRNA splicing, via spliceosome. Each is linked with FOXE3 in more than 7 cancer types. Because this analysis shows association rather than direction, both FOXE3-to-partner and partner-to-FOXE3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXE3→partner) and Y-score (partner→FOXE3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Negative regulation of RNA splicing →	+0.085	+0.737	.001	.009	3	8
KIDNEY	Purine ribonucleoside triphosphate metabolic process →	+0.055	+0.044	.001	<.001	3	7
LUNG_SCLC	Negative regulation of mRNA splicing, via spliceosome →	+0.055	+0.560	.002	.003	3	6
OVARY	Negative regulation of mRNA processing →	+0.063	+0.060	.003	.005	3	6
BLOOD_Leukemia	Regulation of RNA splicing →	+0.047	+0.047	<.001	<.001	3	6
BREAST	Negative regulation of calcium ion export across plasma membrane →	+0.055	+0.069	.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,778 associations by consensus.

Exploration

FOXE3 survival (RNA) · tumor vs normal (RNA) · all FOXE3 data types