Across TCGA patient cohorts, FOXD4L5 mutation is significantly associated with the RNA expression of many other genes, with 184 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible FOXD4L5-associated genes across cancer lineages are OR8U1, RNU6-701P, and SNORD116-19. Each is linked with FOXD4L5 in more than 1 cancer types. Because this analysis shows association rather than direction, both FOXD4L5-to-partner and partner-to-FOXD4L5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXD4L5→partner) and Y-score (partner→FOXD4L5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	OR8U1 →	+0.021	+4.186	<.001	.007	3	2
SKCM	RNU6-701P →	+0.546	+2.725	<.001	.006	3	2
SKCM	SNORD116-19 →	+0.392	+2.856	.002	.004	3	2
BRCA	MIR6074 →	+0.267	+7.731	<.001	.009	3	1
BRCA	RNU6-586P →	+0.267	+7.731	<.001	.009	3	1
UCEC	IGHV3OR16-6 →	+0.558	+2.982	.008	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 184 associations by consensus.

Exploration

FOXD4L5 survival (RNA) · tumor vs normal (RNA) · all FOXD4L5 data types