Across TCGA patient cohorts, FOXD4L5 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FOXD4L5-associated genes across cancer lineages are Macrophages M2, CD8+ naive T-cells, and Th1 cells. Each is linked with FOXD4L5 in more than 1 cancer types. Because this analysis shows association rather than direction, both FOXD4L5-to-partner and partner-to-FOXD4L5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXD4L5→partner) and Y-score (partner→FOXD4L5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Macrophages M2 →	+0.024	+3.118	<.001	.016	2	1
SKCM	CD8+ naive T-cells →	-0.035	-2.980	.041	.037	1	1
UCEC	Th1 cells →	+0.142	+3.000	.008	.037	1	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Exploration

FOXD4L5 survival (RNA) · tumor vs normal (RNA) · all FOXD4L5 data types