Across TCGA patient cohorts, FOXD2 mutation is significantly associated with the RNA expression of many other genes, with 1,089 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FOXD2-associated genes across cancer lineages are POU5F1P2, LINC01758, and RPL31P47. Each is linked with FOXD2 in more than 1 cancer types. Because this analysis shows association rather than direction, both FOXD2-to-partner and partner-to-FOXD2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXD2→partner) and Y-score (partner→FOXD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	POU5F1P2 →	+0.063	+5.899	<.001	.002	3	2
UCEC	LINC01758 →	+0.189	+2.397	<.001	.003	3	2
BLCA	RPL31P47 →	+0.228	+5.177	.001	.007	3	2
UCEC	NUTF2P8 →	+0.121	+2.845	<.001	.001	3	1
UCEC	CHASERR →	+0.647	+3.491	.002	.002	3	1
UCEC	RN7SL248P →	+0.077	+3.606	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,089 associations by consensus.

Exploration

FOXD2 survival (RNA) · tumor vs normal (RNA) · all FOXD2 data types