FOXD1

Across TCGA cell cohorts, FOXD1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,834 significant associations in total. BONE shows the largest number of these associations.

The most reproducible FOXD1-associated GO terms across cancer lineages are Pattern specification involved in metanephros development, Positive regulation of establishment of T cell polarity, and Micturition. Each is linked with FOXD1 in more than 16 cancer types. Because this analysis shows association rather than direction, both FOXD1-to-partner and partner-to-FOXD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Pattern specification involved in metanephros development grouped by FOXD1-low versus FOXD1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXD1→partner) and Y-score (partner→FOXD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Pattern specification involved in metanephros development →	+1.592	+2.691	<.001	<.001	3	17
OVARY	Positive regulation of establishment of T cell polarity →	+0.221	+2.516	<.001	<.001	3	10
BONE	Micturition →	+1.876	+2.845	<.001	<.001	3	9
BONE	Regulation of angiotensin-activated signaling pathway →	+0.202	+2.100	<.001	<.001	3	9
BONE	Negative regulation of bone mineralization involved in bone maturation →	+1.346	+2.183	<.001	<.001	3	9
BREAST	Negative regulation of dendritic cell apoptotic process →	+1.670	+1.886	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,834 associations by consensus.

Pattern specification involved in metanephros development by FOXD1 expression — BONE

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