FOXD1

Across TCGA pan-cancer cohorts, FOXD1 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated FOXD1 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher FOXD1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated FOXD1 expression acts as an unfavorable survival marker, although some lineages such as CESC and LIHC show a favorable association.

ACC, KIRP, and UVM are the cancer types where FOXD1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Median	All	0.194	0.699	<.001	161	view →
KIRP	DFS	Quartile	All	0.518	0.748	<.001	151	view →
UVM	DFS	Median	All	0.387	0.791	<.001	145	view →
HNSC	OS	Median	All	0.282	0.470	<.001	145	view →
MESO	DFS	Median	All	0.265	0.459	<.001	129	view →
KIRC	OS	Median	II,III,IV	0.400	0.644	<.001	84	view →
BLCA	DFS	Median	All	0.446	0.592	.002	61	view →
COAD	OS	Tertile	All	0.327	0.834	.001	58	view →
BRCA	DFS	Quartile	II,III,IV	0.839	0.927	<.001	47	view →
LGG	OS	Median	All	0.360	0.546	<.001	47	view →
THCA	OS	Quartile	All	0.861	1.000	.005	40	view →
LUAD	DFS	Median	IV	0.320	0.660	.003	30	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

FOXD1–ACC (DFS)

Open the ACC breakdown →