Across TCGA patient cohorts, FOXB2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,355 significant associations in total. PRAD shows the largest number of these associations.

The most reproducible FOXB2-associated GO terms across cancer lineages are Methylation, Transcription preinitiation complex assembly, and Positive regulation of DNA repair. Each is linked with FOXB2 in more than 10 cancer types. Because this analysis shows association rather than direction, both FOXB2-to-partner and partner-to-FOXB2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXB2→partner) and Y-score (partner→FOXB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	Methylation →	+0.024	+0.083	<.001	<.001	3	11
LUSC	Transcription preinitiation complex assembly →	+0.025	+0.193	<.001	<.001	3	11
HNSC	Positive regulation of DNA repair →	+0.028	+0.093	<.001	<.001	3	11
DLBC	Nucleoside phosphate biosynthetic process →	+0.089	+0.018	<.001	.007	3	11
LUSC	Obsolete histone modification →	+0.029	+0.283	<.001	<.001	3	10
HNSC	RNA polymerase II preinitiation complex assembly →	+0.028	+0.082	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,355 associations by consensus.

Exploration

FOXB2 survival (RNA) · tumor vs normal (RNA) · all FOXB2 data types