Across TCGA patient cohorts, FOXB2 mutation is significantly associated with the immune_cell of many other genes, with 5 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible FOXB2-associated genes across cancer lineages are Adipocytes, Pericytes, and Th2 cells. Each is linked with FOXB2 in more than 1 cancer types. Because this analysis shows association rather than direction, both FOXB2-to-partner and partner-to-FOXB2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXB2→partner) and Y-score (partner→FOXB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	Adipocytes →	+0.018	+3.094	.033	.017	3	2
LUAD	Pericytes →	+0.067	+2.076	<.001	.032	3	2
LUAD	Th2 cells →	+0.306	+3.011	.001	.020	2	1
LUAD	Macrophages →	+0.053	+3.000	.014	.037	1	1
LUAD	pDC →	+0.063	+3.011	.005	.020	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

FOXB2 survival (RNA) · tumor vs normal (RNA) · all FOXB2 data types