FOXB2

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, FOXB2 RNA expression is significantly associated with the go_rna of many other GO terms, with 210 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible FOXB2-associated GO terms across cancer lineages are Negative regulation of wound healing, Phospholipase C-activating G protein-coupled receptor signaling pathway, and Positive regulation of termination of DNA-templated transcription. Each is linked with FOXB2 in more than 2 cancer types. Because this analysis shows association rather than direction, both FOXB2-to-partner and partner-to-FOXB2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXB2→partner) and Y-score (partner→FOXB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_SCLCNegative regulation of wound healing →-0.115-0.625<.001.00133
LUNG_SCLCPhospholipase C-activating G protein-coupled receptor signaling pathway →-0.057-0.392<.001.00932
SOFT_TISSUEPositive regulation of termination of DNA-templated transcription →+0.082+0.029<.001.00232
SOFT_TISSUEPositive regulation of termination of RNA polymerase II transcription →+0.082+0.029<.001.00232
SOFT_TISSUEPositive regulation of termination of RNA polymerase II transcription, poly(A)-coupled →+0.078+0.029.001.00232
BONEVirion assembly →+0.061+0.013.005.00632
Each partner links to its Q-omics profile. Showing the 6 strongest of 210 associations by consensus.

Exploration