FOXA2

Across TCGA patient cohorts, FOXA2 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,308 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FOXA2-associated proteins across cancer lineages are ASRGL1, CADM1, and COBL_S284. Each is linked with FOXA2 in more than 3 cancer types. Because this analysis shows association rather than direction, both FOXA2-to-partner and partner-to-FOXA2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FOXA2 versus ASRGL1 in OV, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FOXA2→partner) and Y-score (partner→FOXA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ASRGL1 →	+0.785	+1.164	<.001	<.001	3	4
UCEC	CADM1 →	+0.763	+1.993	<.001	<.001	3	4
LUAD	COBL_S284 →	+0.892	+1.072	<.001	<.001	3	4
PDAC	DDAH1 →	+0.551	+1.056	<.001	<.001	3	4
UCEC	PKP4 →	+0.553	+1.613	<.001	<.001	3	4
UCEC	SCARB2 →	+0.425	+1.134	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,308 associations by consensus.

FOXA2 vs ASRGL1 — OV

Explore this scatter interactively →