FOLR3

Across TCGA pan-cancer cohorts, FOLR3 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated FOLR3 data layer compared with 26 for mass-spec protein and 8 for mutation status.

The strongest signal is observed in glioblastoma multiforme (GBM), where higher FOLR3 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated FOLR3 expression acts as an unfavorable survival marker, although some lineages such as GBM and PDAC show a favorable association.

GBM, HNSC, and PDAC are the cancer types where FOLR3 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
GBM	OS	Tertile	All	1.000	0.552	.007	16	view →
HNSC	DFS	Tertile	II,III,IV	0.489	0.973	.013	16	view →
PDAC	OS	Quartile	II,III,IV	0.908	0.330	.017	4	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

FOLR3–GBM (OS)

Open the GBM breakdown →