FOLR3

Across TCGA patient cohorts, FOLR3 mutation is significantly associated with the immune_cell of many other genes, with 6 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FOLR3-associated genes across cancer lineages are MPP, GMP, and NKT. Each is linked with FOLR3 in more than 2 cancer types. Because this analysis shows association rather than direction, both FOLR3-to-partner and partner-to-FOLR3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MPP grouped by FOLR3-low versus FOLR3-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FOLR3→partner) and Y-score (partner→FOLR3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	MPP →	+0.020	+3.809	.011	.018	3	3
STAD	GMP →	+0.150	+3.169	<.001	.049	3	1
UCEC	NKT →	-0.116	-2.989	.030	.035	3	1
UCEC	Basophils →	+0.168	+2.321	.048	.036	2	1
SKCM	iDC →	-0.196	-2.993	.034	.037	1	1
UCEC	pDC →	+0.081	+2.332	<.001	.020	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

MPP by FOLR3 expression — STAD

Explore this box plot interactively →