FOLR2

Across TCGA patient cohorts, FOLR2 mutation is significantly associated with the RNA expression of many other genes, with 631 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FOLR2-associated genes across cancer lineages are MIR98, MTATP6P20, and RNU1-48P. Each is linked with FOLR2 in more than 1 cancer types. Because this analysis shows association rather than direction, both FOLR2-to-partner and partner-to-FOLR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR98 grouped by FOLR2-low versus FOLR2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FOLR2→partner) and Y-score (partner→FOLR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR98 →	+0.461	+2.801	<.001	.005	3	2
SKCM	MTATP6P20 →	+0.059	+4.513	.008	.009	3	2
LUAD	RNU1-48P →	+0.199	+7.930	<.001	.008	3	2
SKCM	MIR629 →	+0.523	+6.098	<.001	<.001	3	2
SKCM	FAM243A →	+0.052	+6.810	<.001	<.001	3	2
READ	PGBD4P2 →	+0.162	+6.257	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 631 associations by consensus.

MIR98 by FOLR2 expression — UCEC

Explore this box plot interactively →