FOLR2

Across TCGA patient cohorts, FOLR2 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FOLR2-associated genes across cancer lineages are cDC, Adipocytes, and Neutrophils. Each is linked with FOLR2 in more than 1 cancer types. Because this analysis shows association rather than direction, both FOLR2-to-partner and partner-to-FOLR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, cDC grouped by FOLR2-low versus FOLR2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FOLR2→partner) and Y-score (partner→FOLR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	cDC →	+0.168	+3.008	<.001	.019	3	2
UCEC	Adipocytes →	+0.036	+2.337	<.001	.010	3	1
UCEC	Neutrophils →	+0.014	+1.681	.002	.049	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

cDC by FOLR2 expression — UCEC

Explore this box plot interactively →