FOLH1

Across TCGA cell cohorts, FOLH1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,678 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible FOLH1-associated GO terms across cancer lineages are L-glutamate biosynthetic process, Regulation of nucleotide-excision repair, and Proton motive force-driven ATP synthesis. Each is linked with FOLH1 in more than 9 cancer types. Because this analysis shows association rather than direction, both FOLH1-to-partner and partner-to-FOLH1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, L-glutamate biosynthetic process grouped by FOLH1-low versus FOLH1-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FOLH1→partner) and Y-score (partner→FOLH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	L-glutamate biosynthetic process →	-0.288	-0.835	<.001	<.001	2	10
LUNG_NSCLC_LUAD	Regulation of nucleotide-excision repair →	+0.050	+0.521	.003	.006	3	7
OVARY	Proton motive force-driven ATP synthesis →	+0.072	+0.940	.008	.006	3	7
OVARY	Retinal ganglion cell axon guidance →	-0.269	-1.079	.001	.004	3	7
LUNG_NSCLC_LUSC	Urokinase plasminogen activator signaling pathway →	-0.825	-1.243	.005	.006	3	7
OVARY	NADH dehydrogenase complex assembly →	+0.042	+0.725	.003	.004	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,678 associations by consensus.

L-glutamate biosynthetic process by FOLH1 expression — BREAST

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