FOLH1

Across TCGA cell cohorts, FOLH1 mutation is significantly associated with the RNA expression of many other genes, with 251 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FOLH1-associated genes across cancer lineages are LGALS16, AURKB, and CABP5. Each is linked with FOLH1 in more than 1 cancer types. Because this analysis shows association rather than direction, both FOLH1-to-partner and partner-to-FOLH1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LGALS16 grouped by FOLH1-low versus FOLH1-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FOLH1→partner) and Y-score (partner→FOLH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	LGALS16 →	+0.148	+4.817	<.001	.001	3	2
LARGE_INTESTINE	AURKB →	+0.539	+2.850	.002	<.001	3	2
SKIN	CABP5 →	+0.012	+4.437	<.001	.004	3	1
SKIN	USP17L17 →	+0.008	+4.437	<.001	.004	3	1
SKIN	DCX →	+0.237	+3.793	<.001	.007	3	1
BLOOD_Leukemia	SMOC2 →	+0.707	+3.676	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 251 associations by consensus.

LGALS16 by FOLH1 expression — LUNG_SCLC

Explore this box plot interactively →