FNTB

Across TCGA patient cohorts, FNTB mutation is significantly associated with the RNA expression of many other genes, with 1,258 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FNTB-associated genes across cancer lineages are RN7SL248P, RNU6-129P, and RNU6-345P. Each is linked with FNTB in more than 2 cancer types. Because this analysis shows association rather than direction, both FNTB-to-partner and partner-to-FNTB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL248P grouped by FNTB-low versus FNTB-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FNTB→partner) and Y-score (partner→FNTB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL248P →	+0.054	+3.059	<.001	.005	3	3
LUSC	RNU6-129P →	+0.748	+5.151	<.001	.007	3	2
COAD	RNU6-345P →	+0.352	+7.741	<.001	.009	3	2
COAD	MIR4535 →	+0.551	+7.741	<.001	.009	3	2
BRCA	MIR6853 →	+0.242	+8.057	<.001	.005	3	1
BLCA	RNU6-164P →	+0.273	+7.640	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,258 associations by consensus.

RN7SL248P by FNTB expression — UCEC

Explore this box plot interactively →