FNTA

Across TCGA patient cohorts, FNTA mutation is significantly associated with the RNA expression of many other genes, with 1,587 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FNTA-associated genes across cancer lineages are RNU6-340P, MIR7702, and RNU6-669P. Each is linked with FNTA in more than 2 cancer types. Because this analysis shows association rather than direction, both FNTA-to-partner and partner-to-FNTA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-340P grouped by FNTA-low versus FNTA-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FNTA→partner) and Y-score (partner→FNTA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-340P →	+0.167	+2.912	<.001	.009	3	3
UCEC	MIR7702 →	+0.229	+4.253	<.001	.004	3	2
SKCM	RNU6-669P →	+0.323	+6.624	<.001	.001	3	2
SKCM	TBC1D3P4 →	+0.033	+5.513	.001	.004	3	2
UCEC	SPCS2P2 →	+0.064	+2.798	<.001	.001	3	1
UCEC	NUDT4P2 →	+0.053	+2.899	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,587 associations by consensus.

RNU6-340P by FNTA expression — UCEC

Explore this box plot interactively →