FNDC8

Across TCGA patient cohorts, FNDC8 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,875 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FNDC8-associated proteins across cancer lineages are FEN1, TLK2, and ZNF318_S1896. Each is linked with FNDC8 in more than 3 cancer types. Because this analysis shows association rather than direction, both FNDC8-to-partner and partner-to-FNDC8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FNDC8 versus FEN1 in GBM, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FNDC8→partner) and Y-score (partner→FNDC8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	FEN1 →	+0.565	+0.276	<.001	<.001	3	4
HNSC	TLK2 →	+0.228	+0.338	.001	.006	3	4
LSCC	ZNF318_S1896 →	+0.510	+0.223	.002	<.001	3	3
GBM	SF3B6 →	+0.196	+0.211	<.001	<.001	3	3
LSCC	GTF3C2 →	+0.339	+0.375	<.001	<.001	3	3
GBM	AMPD3 →	-0.468	-0.188	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,875 associations by consensus.

FNDC8 vs FEN1 — GBM

Explore this scatter interactively →