FNDC4

Across TCGA patient cohorts, FNDC4 protein abundance is significantly associated with the RNA expression of many other genes, with 747 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible FNDC4-associated genes across cancer lineages are KCNJ4, MIR4803, and PNPLA5. Each is linked with FNDC4 in more than 1 cancer types. Because this analysis shows association rather than direction, both FNDC4-to-partner and partner-to-FNDC4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FNDC4 versus KCNJ4 in GBM, with a Pearson correlation of 0.87.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FNDC4→partner) and Y-score (partner→FNDC4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	KCNJ4 →	+2.369	+0.844	.001	.008	3	2
CCRCC	MIR4803 →	-1.590	-0.474	.007	.005	3	2
GBM	PNPLA5 →	+0.889	+1.160	<.001	.009	3	1
GBM	PDYN →	+3.127	+0.844	.007	.008	3	1
GBM	SLC32A1 →	+2.180	+0.844	.004	.008	3	1
GBM	SYP →	+2.696	+1.160	.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 747 associations by consensus.

FNDC4 vs KCNJ4 — GBM

Explore this scatter interactively →