FNDC3A

Across TCGA patient cohorts, FNDC3A protein abundance is significantly associated with the RNA expression of many other genes, with 16,024 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FNDC3A-associated genes across cancer lineages are BHLHA15, HDAC5, and FKBP11. Each is linked with FNDC3A in more than 5 cancer types. Because this analysis shows association rather than direction, both FNDC3A-to-partner and partner-to-FNDC3A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FNDC3A versus BHLHA15 in PDAC, with a Pearson correlation of 0.54.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FNDC3A→partner) and Y-score (partner→FNDC3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	BHLHA15 →	+1.476	+0.242	<.001	<.001	3	6
LUAD	HDAC5 →	-0.512	-0.412	<.001	<.001	3	6
HNSC	FKBP11 →	+0.570	+0.336	<.001	<.001	3	6
HNSC	SURF2 →	-0.652	-0.256	.009	.001	2	6
BRCA	SSR4 →	+0.636	+0.358	<.001	<.001	3	5
LSCC	IQANK1 →	-0.880	-0.310	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,024 associations by consensus.

FNDC3A vs BHLHA15 — PDAC

Explore this scatter interactively →