FNDC3A

Across TCGA patient cohorts, FNDC3A mutation is significantly associated with the RNA expression of many other genes, with 5,196 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FNDC3A-associated genes across cancer lineages are MRPL51P2, IGHD3-16, and RPL30P13. Each is linked with FNDC3A in more than 2 cancer types. Because this analysis shows association rather than direction, both FNDC3A-to-partner and partner-to-FNDC3A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MRPL51P2 grouped by FNDC3A-low versus FNDC3A-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FNDC3A→partner) and Y-score (partner→FNDC3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	MRPL51P2 →	+0.138	+7.169	<.001	<.001	3	3
HNSC	IGHD3-16 →	+1.501	+3.818	<.001	.009	3	3
LUSC	RPL30P13 →	+0.148	+2.694	<.001	.007	3	3
UCEC	VDAC2 →	+0.349	+1.546	.007	.001	3	3
UCEC	ELP5 →	+0.358	+2.648	<.001	<.001	3	3
UCEC	TIMM22 →	+0.461	+3.182	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,196 associations by consensus.

MRPL51P2 by FNDC3A expression — LIHC

Explore this box plot interactively →