FNDC3A

Across TCGA cell cohorts, FNDC3A RNA expression is significantly associated with the go_rna of many other GO terms, with 2,975 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FNDC3A-associated GO terms across cancer lineages are Endoplasmic reticulum mannose trimming, Negative regulation of hematopoietic stem cell differentiation, and Retrograde transport, vesicle recycling within Golgi. Each is linked with FNDC3A in more than 13 cancer types. Because this analysis shows association rather than direction, both FNDC3A-to-partner and partner-to-FNDC3A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endoplasmic reticulum mannose trimming grouped by FNDC3A-low versus FNDC3A-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FNDC3A→partner) and Y-score (partner→FNDC3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Endoplasmic reticulum mannose trimming →	+0.117	+1.007	.002	.003	2	14
BLOOD_Myeloma	Negative regulation of hematopoietic stem cell differentiation →	+0.198	+1.233	.001	<.001	3	13
STOMACH	Retrograde transport, vesicle recycling within Golgi →	+0.126	+1.021	<.001	<.001	3	12
BLOOD_Myeloma	Protein demannosylation →	+0.122	+1.168	.002	.001	2	13
BLOOD_Myeloma	Protein alpha-1,2-demannosylation →	+0.122	+1.168	.002	.001	2	13
BREAST	Ribosomal protein import into nucleus →	+0.085	+0.648	.002	.003	2	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,975 associations by consensus.

Endoplasmic reticulum mannose trimming by FNDC3A expression — BLOOD_Myeloma

Explore this box plot interactively →