FNDC3A

Across TCGA cell cohorts, FNDC3A mutation is significantly associated with the RNA expression of many other genes, with 175 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FNDC3A-associated genes across cancer lineages are GCAT, CBY1, and PSMC6. Each is linked with FNDC3A in more than 1 cancer types. Because this analysis shows association rather than direction, both FNDC3A-to-partner and partner-to-FNDC3A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GCAT grouped by FNDC3A-low versus FNDC3A-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FNDC3A→partner) and Y-score (partner→FNDC3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	GCAT →	+1.385	+3.364	<.001	.002	3	1
LARGE_INTESTINE	CBY1 →	+0.666	+3.160	<.001	.006	3	1
LARGE_INTESTINE	PSMC6 →	+0.459	+3.064	.004	.009	3	1
LARGE_INTESTINE	ARMC1 →	+0.390	+3.067	.008	.009	3	1
LARGE_INTESTINE	C6orf118 →	+0.095	+2.600	<.001	.001	3	1
LARGE_INTESTINE	ARL1 →	+0.513	+3.304	.003	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 175 associations by consensus.

GCAT by FNDC3A expression — LARGE_INTESTINE

Explore this box plot interactively →