FNDC11

Across TCGA patient cohorts, FNDC11 mutation is significantly associated with the RNA expression of many other genes, with 384 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FNDC11-associated genes across cancer lineages are FAM207CP, RNA5SP412, and DUX4L46. Each is linked with FNDC11 in more than 1 cancer types. Because this analysis shows association rather than direction, both FNDC11-to-partner and partner-to-FNDC11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM207CP grouped by FNDC11-low versus FNDC11-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FNDC11→partner) and Y-score (partner→FNDC11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	FAM207CP →	+0.089	+5.970	<.001	.002	3	2
UCEC	RNA5SP412 →	+0.592	+2.481	.002	.006	3	2
CESC	DUX4L46 →	+0.058	+5.103	<.001	.008	3	2
CESC	RN7SL726P →	+0.186	+5.306	.002	.006	3	2
LUAD	RNU6-18P →	+0.560	+5.554	<.001	.004	3	2
UCEC	RNU6-672P →	+0.546	+3.152	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 384 associations by consensus.

FAM207CP by FNDC11 expression — SKCM

Explore this box plot interactively →