FNDC1-IT1

Across TCGA pan-cancer cohorts, FNDC1-IT1 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated FNDC1-IT1 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher FNDC1-IT1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated FNDC1-IT1 expression acts as an unfavorable survival marker, although some lineages such as DLBC and LIHC show a favorable association.

ACC, KIRP, and MESO are the cancer types where FNDC1-IT1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Tertile	IV	0.048	0.380	<.001	98	view →
KIRP	OS	Quartile	II,III,IV	0.505	0.800	.002	42	view →
MESO	OS	Tertile	All	0.310	0.564	.006	40	view →
THYM	OS	Tertile	All	0.807	1.000	<.001	30	view →
KICH	OS	Tertile	III,IV	0.178	0.847	<.001	18	view →
DLBC	DFS	Median	II,III,IV	1.000	0.665	.005	16	view →
COAD	DFS	Tertile	All	0.735	0.808	.028	15	view →
ESCA	OS	Quartile	IV	0.095	0.597	.045	12	view →
PAAD	OS	Quartile	All	0.238	0.546	.010	11	view →
HNSC	DFS	Tertile	All	0.544	0.685	.028	11	view →
KIRC	DFS	Quartile	II,III,IV	0.380	0.555	.011	10	view →
LIHC	DFS	Tertile	III,IV	0.698	0.318	.031	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

FNDC1-IT1–ACC (DFS)

Open the ACC breakdown →