FNBP4

Across TCGA pan-cancer cohorts, FNBP4 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated FNBP4 data layer compared with 26 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher FNBP4 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated FNBP4 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and PDAC show a favorable association.

CCRCC, HNSC, and PDAC are the cancer types where FNBP4 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Median	IV	0.781	0.220	.017	3	view →
HNSC	DFS	Median	IV	0.578	0.819	.038	2	view →
PDAC	OS	Quartile	III,IV	0.858	0.594	.049	2	view →
UCEC	OS	Tertile	All	0.974	0.825	.029	2	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

FNBP4–CCRCC (DFS)

Open the CCRCC breakdown →