FNBP4

Across TCGA patient cohorts, FNBP4 mutation is significantly associated with the RNA expression of many other genes, with 4,103 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FNBP4-associated genes across cancer lineages are RAD17, CC2D1B, and FAXDC2. Each is linked with FNBP4 in more than 2 cancer types. Because this analysis shows association rather than direction, both FNBP4-to-partner and partner-to-FNBP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RAD17 grouped by FNBP4-low versus FNBP4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FNBP4→partner) and Y-score (partner→FNBP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RAD17 →	+0.414	+2.684	<.001	<.001	3	3
UCEC	CC2D1B →	+0.210	+1.595	.003	.001	3	3
UCEC	FAXDC2 →	-0.457	-2.392	.005	<.001	3	3
UCEC	FAM98B →	+0.360	+1.389	.004	.005	3	3
UCEC	BNIP3 →	+0.639	+1.807	.001	<.001	3	3
UCEC	PITHD1 →	+0.320	+2.354	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,103 associations by consensus.

RAD17 by FNBP4 expression — UCEC

Explore this box plot interactively →