FNBP4

Across TCGA patient cohorts, FNBP4 mutation is significantly associated with the total protein of many other genes, with 50 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FNBP4-associated genes across cancer lineages are ATM, FASN, and TFRC. Each is linked with FNBP4 in more than 3 cancer types. Because this analysis shows association rather than direction, both FNBP4-to-partner and partner-to-FNBP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATM grouped by FNBP4-low versus FNBP4-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FNBP4→partner) and Y-score (partner→FNBP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	ATM →	-0.442	-3.169	.010	.018	3	4
COAD	FASN →	+0.506	+2.815	.018	.036	3	3
UCEC	TFRC →	+0.505	+2.700	.001	.005	3	3
UCEC	Cyclin-B1 →	+0.578	+2.584	<.001	<.001	3	3
BLCA	ACC_pS79 →	+0.360	+3.321	.029	.009	3	2
BLCA	ACVRL1 →	-0.177	-2.296	.036	.033	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 50 associations by consensus.

ATM by FNBP4 expression — BLCA

Explore this box plot interactively →