FNBP4

Across TCGA cell cohorts, FNBP4 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,828 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FNBP4-associated GO terms across cancer lineages are Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway, Positive regulation of DNA metabolic process, and Regulation of telomere maintenance. Each is linked with FNBP4 in more than 16 cancer types. Because this analysis shows association rather than direction, both FNBP4-to-partner and partner-to-FNBP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway grouped by FNBP4-low versus FNBP4-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FNBP4→partner) and Y-score (partner→FNBP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway →	+0.198	+1.362	<.001	<.001	3	17
BONE	Positive regulation of DNA metabolic process →	+0.115	+1.539	<.001	<.001	3	17
BONE	Regulation of telomere maintenance →	+0.071	+0.911	<.001	<.001	3	17
BONE	Negative regulation of translational initiation →	+0.153	+1.149	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Negative regulation of autophagy →	+0.080	+1.117	<.001	.004	3	16
UPPER_AERODIGESTIVE_TRACT	Promoter clearance during DNA-templated transcription →	+0.132	+1.229	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,828 associations by consensus.

Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway by FNBP4 expression — BONE

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