FNBP1L

Across TCGA pan-cancer cohorts, FNBP1L Mutation is linked to patient survival in 6 of 34 cancer types, making it a survival-associated FNBP1L data layer compared with 24 for mass-spec protein and 7 for mass-spec protein.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher FNBP1L Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated FNBP1L expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

KIRC, KIRP, and UCEC are the cancer types where FNBP1L Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.062	0.874	<.001	36	view →
KIRP	DFS	Median	All	0.176	0.829	<.001	21	view →
UCEC	DFS	Median	III,IV	0.952	0.775	.028	16	view →
BLCA	DFS	Median	IV	0.090	0.469	.009	12	view →
SKCM	OS	Median	All	0.350	0.784	.008	12	view →
PRAD	DFS	Median	All	0.085	0.774	<.001	6	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

FNBP1L–KIRC (OS)

Open the KIRC breakdown →