FNBP1L

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, FNBP1L mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated FNBP1L data layer compared with 24 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher FNBP1L mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated FNBP1L expression acts as an unfavorable survival marker, although some lineages such as COAD and UCEC show a favorable association.

COAD, UCEC, and GBM are the cancer types where FNBP1L mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
COADDFSTertileAll1.0000.877.01172view →
UCECDFSMedianII,III,IV0.9250.476.00248view →
GBMOSMedianAll0.5260.272.0066view →
PDACOSMedianAll0.2850.547.0036view →
CCRCCDFSTertileIII,IV0.7800.435.0245view →
LSCCDFSMedianIII,IV0.5840.984.0314view →
LUADOSQuartileIII,IV0.9930.618.0403view →
Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

FNBP1L–COAD (DFS)

Kaplan–Meier survival curve for FNBP1L mass-spec protein-high vs -low samples in COAD.

Open the COAD breakdown →

Exploration