FN3KRP

Across TCGA pan-cancer cohorts, FN3KRP mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated FN3KRP data layer compared with 25 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher FN3KRP mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated FN3KRP expression acts as an unfavorable survival marker, although some lineages such as CCRCC and PDAC show a favorable association.

CCRCC, PDAC, and COAD are the cancer types where FN3KRP mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Quartile	III,IV	0.912	0.500	.008	18	view →
PDAC	OS	Median	III,IV	0.813	0.350	.006	14	view →
COAD	DFS	Median	III,IV	0.890	1.000	.030	12	view →
LSCC	DFS	Quartile	II,III,IV	1.000	0.250	.024	4	view →
LUAD	DFS	Median	III,IV	1.000	0.498	.017	3	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

FN3KRP–CCRCC (DFS)

Open the CCRCC breakdown →