FN3KRP

Across TCGA patient cohorts, FN3KRP mutation is significantly associated with the RNA expression of many other genes, with 152 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FN3KRP-associated genes across cancer lineages are RPL32P19, RNA5SP351, and RNU7-175P. Each is linked with FN3KRP in more than 1 cancer types. Because this analysis shows association rather than direction, both FN3KRP-to-partner and partner-to-FN3KRP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPL32P19 grouped by FN3KRP-low versus FN3KRP-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FN3KRP→partner) and Y-score (partner→FN3KRP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RPL32P19 →	+0.355	+5.017	<.001	.009	3	2
LUAD	RNA5SP351 →	+0.503	+4.243	.001	.008	3	2
LUAD	RNU7-175P →	+0.680	+4.821	.008	.003	3	2
HNSC	CTHRC1P1 →	+0.127	+5.822	<.001	.003	3	2
HNSC	TRAJ52 →	+0.439	+5.241	<.001	.007	3	2
UCEC	TRAJ21 →	+0.994	+3.936	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 152 associations by consensus.

RPL32P19 by FN3KRP expression — COAD

Explore this box plot interactively →