FN3KRP

Across TCGA patient cohorts, FN3KRP mutation is significantly associated with the total protein of many other genes, with 6 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FN3KRP-associated genes across cancer lineages are Myosin-IIa, SF2, and IGFBP2. Each is linked with FN3KRP in more than 1 cancer types. Because this analysis shows association rather than direction, both FN3KRP-to-partner and partner-to-FN3KRP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Myosin-IIa grouped by FN3KRP-low versus FN3KRP-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FN3KRP→partner) and Y-score (partner→FN3KRP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Myosin-IIa →	+0.222	+3.007	.038	.019	2	1
UCEC	SF2 →	-0.129	-2.986	.042	.037	2	1
UCEC	IGFBP2 →	-0.917	-3.000	.014	.037	1	1
UCEC	MSH6 →	-0.632	-3.000	<.001	.037	1	1
UCEC	PDK1_pS241 →	+0.272	+3.013	.005	.019	1	1
UCEC	Annexin-1 →	+0.918	+3.000	.002	.037	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

Myosin-IIa by FN3KRP expression — UCEC

Explore this box plot interactively →