FN3KRP

Across TCGA cell cohorts, FN3KRP RNA expression is significantly associated with the go_rna of many other GO terms, with 3,438 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible FN3KRP-associated GO terms across cancer lineages are Positive regulation of mitotic cytokinesis, Negative regulation of cell cycle process, and Mitotic G2/M transition checkpoint. Each is linked with FN3KRP in more than 15 cancer types. Because this analysis shows association rather than direction, both FN3KRP-to-partner and partner-to-FN3KRP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of mitotic cytokinesis grouped by FN3KRP-low versus FN3KRP-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FN3KRP→partner) and Y-score (partner→FN3KRP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Positive regulation of mitotic cytokinesis →	+0.166	+0.971	.001	<.001	3	16
BLOOD_Lymphoma	Negative regulation of cell cycle process →	+0.059	+1.111	<.001	<.001	3	15
SOFT_TISSUE	Mitotic G2/M transition checkpoint →	+0.073	+0.538	<.001	<.001	3	15
BREAST	Cell cycle checkpoint signaling →	+0.059	+0.574	.002	.008	3	14
UPPER_AERODIGESTIVE_TRACT	Negative regulation of mitotic cell cycle →	+0.080	+1.073	.002	.004	3	14
OVARY	DTMP biosynthetic process →	+0.189	+0.977	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,438 associations by consensus.

Positive regulation of mitotic cytokinesis by FN3KRP expression — BREAST

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